With every day that passed he became ever more despairing.

　　隨著日子一天天過去，他越來越絕望。

　　One harsh word would send her into the depths of despair.

　　一句嚴厲的話就會使她陷入極度的絕望之中。

　　Don't despair! We'll think of a way out of this.

　　別灰心！我們會找到出路的。

　　The book describes a spiritual journey from despair to happiness.

　　這本書描述了從絕望到高興的心理變化過程。

　　They'd almost despaired of ever having children.

　　他們對生孩子幾乎不抱任何希望了。